Skip to main content
Health & Medicine

Strengthening health systems to prioritise, provide care, and prevent osteoarthritis: a roadmap for global health policy.

| Source: Lancet (London, England)

By 2050, almost 1 billion people are expected to live with osteoarthritis-a disabling musculoskeletal condition with currently no cure. Despite its burden and costs, osteoarthritis remains largely invisible in national and global health agendas, is poorly integrated within service models for other chronic health conditions, and is frequently perceived as inevitable with ageing and associated with limited therapeutic options. This context drives an osteoarthritis identity problem that fuels frust

By 2050, almost 1 billion people are expected to live with osteoarthritis-a disabling musculoskeletal condition with currently no cure. Despite its burden and costs, osteoarthritis remains largely invisible in national and global health agendas, is poorly integrated within service models for other chronic health conditions, and is frequently perceived as inevitable with ageing and associated with limited therapeutic options. This context drives an osteoarthritis identity problem that fuels frustration among those living with the disease and health-care professionals, perpetuates stigma and inequities, undermines access to effective interventions, and crucially, deprioritises osteoarthritis in health policy. How can health systems be strengthened to mitigate the burden of disease and prioritise the prevention and control of osteoarthritis? We outline a co-created, globally relevant roadmap for health policy responses for osteoarthritis prevention and care that extend beyond the UN's Agenda 2030 targets. The intended audience for the roadmap includes health policy makers, health services managers, clinicians, and civil society organisations. The roadmap anchors to three strategic priorities underpinned by guiding principles of a life course approach, prioritising health equity, and ensuring that responses are affordable and sustainable across economies. Priority 1: recognise and respond to osteoarthritis with capacity building in national surveillance of burden, cost, and modifiable risk factors, and explicitly embedding musculoskeletal health within national and subnational health policies. Priority 2: scale up high-value, person-centred, equitable care for approximately 600 million people living with osteoarthritis. This priority requires reframing of societal narratives around osteoarthritis and reconfiguring service models to integrate osteoarthritis into primary and chronic disease care while also addressing social, environmental, and commercial determinants of musculoskeletal health. Priority 3: slow the osteoarthritis trajectory via primary and secondary prevention targeted at excess bodyweight and joint injury, enabled by cross-sectoral and cross-disease cooperation. These priorities are supported by accelerators requiring global collaboration, within and outside the osteoarthritis community.

Read the original source →

Related Topics

Related Stories

Health & Medicine

The honey bee stinger: An unusual pump with collapsible double pistons.

Most stinging animals deliver venom by contracting muscles around a venom reservoir, but honey bees employ a fundamentally different strategy. The stingers of worker bees have the unique ability to autotomize, separating from the body, to continue to sting independently. Despite more than a century of anatomical descriptions, the mechanics of venom pumping have remained unresolved due to the challenges of observing them in action. We recorded high-speed videos of active, autotomized stingers, co

Continue reading
Health & Medicine

Chronic cigarette smoke exposure induces distinct stem cell states driving genetic driver-specific non-small cell lung cancer subtypes.

Cigarette smoke-induced chronic inflammation (CI) potentiates development of non-small cell lung cancer (NSCLC) by mediating genetic and epigenetic events. Using normal lung organoids (LOs), we define how chronic cigarette smoke condensate (CSC) exposure drives two separate stem cell populations to evolve premalignant states harboring progressive epigenetic and linked transcriptomic abnormalities in the absence of major driver mutations. These dynamics facilitate evolution of an immune evasive s

Continue reading
Health & Medicine

Extended fractional Hofstadter states at high field in twisted bilayer graphene above the magic angle.

When a Chern band is partially filled, a fractional Chern insulator (FCI)-the lattice analog of a fractional quantum Hall state-can arise. Though the full range of possible scenarios for producing such a state is not established, the most tractable models combine strong electronic interactions with the quantum geometry of the parent Chern band meeting specific criteria. In twisted bilayer graphene, the importance of interactions can be tuned by varying the interlayer twist. Here, we study a samp

Continue reading
Health & Medicine

Phenotypic screening identifies kenpaullone as a prolymphangiogenic compound to improve heart repair following myocardial infarction.

Myocardial infarction (MI) induces cardiac muscle death and its subsequent replacement by a noncontractile fibrotic scar, which underlies progression to heart failure. Current treatments restore blood flow and assist with cardiac workload but do not promote regeneration. We have previously shown endogenous growth of the cardiac lymphatic system following MI and further stimulation with the lymphatic endothelial specific mutated Vascular Endothelial Growth Factor-C (VEGF-C) isoform, VEGFC-C156S,

Continue reading
Health & Medicine

Dopamine suppresses pathological retinal oscillations and enhances the signal-to-noise ratio.

Infantile nystagmus is a debilitating involuntary eye movement disorder often associated with retinal diseases such as congenital stationary night blindness (CSNB). The oscillating eye movements of infantile nystagmus come with reduced visual acuity and strongly impair quality of life. No cure exists for this condition. Previously, we demonstrated that nystagmus in the CSNB mouse model Nyx nob has a retinal cause. Specifically, we found that synchronized oscillations of retinal ganglion cells (R

Continue reading